QuickView for Yin Yang 1;jsessionid=C3AE44587D1ED8C955E1C15299D92BBC;jsessionid=E6403A7BE438693C4BEC8DCBC3298FD5 (gene)
- Gene Symbol:
- YY1
Homo sapiens - Full name:
- YY1 transcription factor
- Synonyms:
- DELTA, GADEVS, INO80S, NF-E1, UCRBP, YIN-YANG-1, transcriptional repressor protein YY1, INO80 complex subunit S, YY-1, Yin and Yang 1 protein, delta transcription factor
- Genomic Location:
- Chr 14: 99774855-99814557
- Description:
-
YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histon...
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Bos taurus , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan): -
Predicted Gene Targets for miR-142-5p , Predicted Gene Targets for miR-181 , Predicted Gene Targets for miR-186 , Predicted Gene Targets for miR-141 , Predicted Gene Targets for miR-34 , Predicted Gene Targets for miR-381 , Predicted Gene Targets for miR-433-3p , Predicted Gene Targets for miR-29 , Predicted Gene Targets for miR-384 , Predicted Gene Targets for miR-410
- Cytogenetic Map:
-
14q32.2
GO Molecular Function
sequence-specific DNA binding | transcription factor activity, transcription factor binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | enhancer binding | cation binding | repressing transcription factor binding | DNA secondary structure binding | transcription factor activity, RNA polymerase II transcription factor binding | proximal promoter sequence-specific DNA binding | enzyme binding | nucleic acid binding | four-way junction DNA binding | transcriptional repressor activity, RNA polymerase II transcription factor binding | enhancer sequence-specific DNA binding | RNA polymerase II repressing transcription factor binding | RNA polymerase II regulatory region DNA binding | DNA binding | sequence-specific double-stranded DNA binding | transcription corepressor activity | transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | ion binding | organic cyclic compound binding | transcription coactivator activity | transcription regulatory region sequence-specific DNA binding | protein binding | zinc ion binding | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | DNA-binding transcription factor activity | transcription factor binding | RNA polymerase II transcription factor binding | RNA polymerase II regulatory region sequence-specific DNA binding | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | RNA polymerase II distal enhancer sequence-specific DNA binding | transition metal ion binding | histone deacetylase binding | transcription coregulator activity | SMAD binding | metal ion binding | heterocyclic compound binding | RNA binding
GO Biological Process
protein modification by small protein removal | RNA metabolic process | double-strand break repair | response to radiation | transcription factor activity, transcription factor binding | positive regulation of macromolecule biosynthetic process | response to cytokine | response to interleukin-1 | negative regulation of type I interferon production | proteolysis | eye development | response to hormone | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | negative regulation of RNA biosynthetic process | cell differentiation | male gamete generation | pattern specification process | positive regulation of cellular biosynthetic process | cellular process | localization | multicellular organismal reproductive process | negative regulation of nucleic acid-templated transcription | macromolecule localization | positive regulation of nitrogen compound metabolic process | transcription factor activity, RNA polymerase II transcription factor binding | negative regulation of cellular metabolic process | gamete generation | response to prostaglandin | regulation of interferon-beta production | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular component organization | protein deubiquitination | response to UV | regulation of type I interferon production | response to stimulus | transcriptional repressor activity, RNA polymerase II transcription factor binding | cellular response to light stimulus | response to stress | cellular nitrogen compound biosynthetic process | reproduction | cellular nitrogen compound metabolic process | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | protein modification process | cellular biosynthetic process | DNA recombination | macromolecule modification | DNA repair | anterior/posterior pattern specification | regulation of nucleic acid-templated transcription | response to light stimulus | system development | nitrogen compound metabolic process | reproductive process | double-strand break repair via homologous recombination | multicellular organism development | response to fatty acid | cellular response to DNA damage stimulus | regulation of gene expression | cellular response to stress | response to lipid | negative regulation of cytokine production | positive regulation of cellular metabolic process | cellular response to radiation | animal organ morphogenesis | regulation of pri-miRNA transcription by RNA polymerase II | regulation of nitrogen compound metabolic process | transcription corepressor activity | regulation of transcription by RNA polymerase II | transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | cellular response to cytokine stimulus | biosynthetic process | aromatic compound biosynthetic process | cellular response to UV | sensory organ development | regulation of cellular metabolic process | eye morphogenesis | transcription coactivator activity | regulation of RNA metabolic process | response to prostaglandin F | negative regulation of interferon-beta production | multicellular organism reproduction | protein metabolic process | DNA-binding transcription factor activity | regionalization | response to organic substance | DNA metabolic process | anatomical structure development | metabolic process | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | gene expression | protein modification by small protein conjugation or removal | transcription, DNA-templated | camera-type eye development | regulation of transcription, DNA-templated | response to UV-C | cellular protein metabolic process | regulation of cytokine production | anatomical structure morphogenesis | cellular macromolecule biosynthetic process | camera-type eye morphogenesis | recombinational repair | developmental process | organelle organization | cellular response to interleukin-1 | spermatogenesis | cellular protein modification process | negative regulation of transcription by RNA polymerase II | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | transcription coregulator activity | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | positive regulation of metabolic process | chromosome organization | cellular metabolic process | cellular response to organic substance | RNA localization | sexual reproduction | negative regulation of pri-miRNA transcription by RNA polymerase II | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
PcG protein complex | chromosome | intracellular membrane-bounded organelle | catalytic complex | cell | nuclear lumen | transcription factor complex | cytoplasm | intracellular organelle | protein-containing complex | nucleoplasm | chromatin | nuclear chromosome | Ino80 complex | membrane-bounded organelle | nucleus | organelle | SWI/SNF superfamily-type complex | membrane-enclosed lumen | nuclear matrix | nuclear chromatin | ATPase complex | intracellular | nuclear periphery
